l-Proline-catalyzed three-component synthesis of condensed imidazoles
نویسندگان
چکیده
منابع مشابه
L-Proline catalyzed synthesis of Betti bases and biscoumarin derivatives
The direct three component modified Mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate Betti bases has been carried out over L-proline (20 mol%) with high efficiency under solvent free conditions at 70 OC. Also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of L-proline (20 mol%) in the ethanol under reflux condi...
متن کاملL-proline catalyzed synthesis of naphthopyranopyrimidines via multicomponent reaction
A green and efficient one pot, three component protocol for synthesis of naphthopyranopyrimidines by cyclocondensation of β-naphthol, aldehyde, and 6-amino-1,3-dimethyluracil using L-proline as a beneficial catalyst with high catalytic activity under solvent-free conditions at 100 °C is described. In this study, several types of aromatic aldehyde, containing electron-withdrawing groups as well ...
متن کاملL-proline catalyzed synthesis of naphthopyranopyrimidines via multicomponent reaction
A green and efficient one pot, three component protocol for synthesis of naphthopyranopyrimidines by cyclocondensation of β-naphthol, aldehyde, and 6-amino-1,3-dimethyluracil using L-proline as a beneficial catalyst with high catalytic activity under solvent-free conditions at 100 °C is described. In this study, several types of aromatic aldehyde, containing electron-withdrawing groups as well ...
متن کاملL-Proline catalyzed synthesis of Betti bases and biscoumarin derivatives
The direct three component modified Mannich reaction via condensation of aldehydes, 2-naphthol or 2,7-naphthalendiol and piperidine to generate Betti bases has been carried out over L-proline (20 mol%) with high efficiency under solvent free conditions at 70 OC. Also, the reaction of aromatic aldehyde and 4-hydroxycoumarin in the presence of L-proline (20 mol%) in the ethanol under reflux condi...
متن کاملL-proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines.
Highly functionalized multisubstituted 1,4-dihydropyridines 5 have been concisely synthesized in moderate to good yields via L-proline-catalyzed one-pot multicomponent reactions (MCRs) of alkynoates or alkynones 1, amines 2, beta-dicarbonyl compounds 3 and aldehydes 4 under mild conditions. The MCR process involves hydroamination/Knoevenagel condensation/Michael-type addition/intramolecular cyc...
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ژورنال
عنوان ژورنال: Arabian Journal of Chemistry
سال: 2016
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2011.12.004